Three Of A Kind: Fibrates

Fibrates, which are derived from fibric acid, are used to increase good cholesterol and decrease bad cholesterol in people who need to keep their high cholesterol under control. These medications lower the levels of fat in the blood that are the cause of dangerous high cholesterol levels. There are three types of fibrates-gemfibrozil, fenofibrate, and clofibrate. Each has its own unique characteristics that can lower high cholesterol, and your doctor will choose the one that will be safest and most effective for you. In those with very high levels of cholesterol in their body, these may be prescribed along with statins. No official studies have been done to compare each of the three medications. However each has unique side effects that may be important to patients with more than just high cholesterol problems.

Gemfibrozil is shown to reduce the risk of heart attack from high cholesterol or coronary artery disease. It is also effective in reducing the factors of those suffering from or in risk of developing metabolic syndrome. Fenofibrate has the lowest chance of side effects in the three medications. It is the safest to take with statins because it does not interfere with your bodies' ability to break them down. Clofibrate is the most dangerous and least prescribed of the three fibrates, but is prescribed when the other two medications do not effectively lower high cholesterol levels in the patient. The dangerous side effects include developing bile duct cancer and frequent gallstones.

This type of medication is usually recommended to those who have high levels of triglycerides. If not under control, this can cause diabetes, heart disease, and an under-active thyroid gland among many other dangerous conditions. Lifestyle changes are also part of high cholesterol therapy using fibrates. Saturated fats should be cut out of the diet completely, and high carbohydrates should also be avoided. Regular exercise will also keep the body in good shape while combating the bad cholesterol that is present.

Food, lifestyle, and genetics are the causing factors of dangerously high cholesterol levels in the body. Your doctor will decide if fibrates are ideal for your symptoms based on your needs and risk level. The side effects of fibrates are moderately low depending on which medication is prescribed to you. If your doctor decides that it is also necessary for you to take statins, some of the risk for certain side effects could be increased and it is always recommended that you stay under constant supervision of a doctor.

More Articles

Using Cholesterol Absorption Inhibitors

... combine together to form bile salt micelles. These salt micelles work in attracting cholesterol and are then absorbed by the intestine. After they are absorbed, they are headed back through the bloodstream to the liver where they are then secreted back into the blood as VLDL particles, precursors to low ...

Read Full Article  

What Are Bile Acid Sequestrants?

... cholesterol can be tricky. Scientists have found that in order to win this battle, sometimes you must out-trick the trickster. Bile acid sequestrants do just that. While they may not be as effective as using other methods, using them in combination with other medications has proven to reduce cholesterol ...

Read Full Article  

Exercising To Lower Your Cholesterol

... first. In this way, losing weight can help reduce cholesterol significantly by eliminating those fats that help clog the arteries and increase LDL levels. You do not have to start lifting 20 pound weights, though. You can buy small 1, 2, or 3 pound wrist bands that can wrap around your wrist or ankle; ...

Read Full Article  

Fats And Your Cholesterol

... cholesterol levels. They are often found in meat fats, such as dairy products like butter, cream, or ice cream. These fats can also be found on pieces of meat to be cooked and can be removed simply by cutting them off before cooking. While certain oils like canola oil or olive oil are acceptable for a ...

Read Full Article  

What Is A Stroke?

... a stroke that affects the right part of your brain you will be at risk of losing vision. One the other hand, strokes affecting the left side may cause speech problems as a result. Any brain cells that die will cause memory loss and paralysis that may take over parts or the entire side of your body. High ...

Read Full Article